California
San Francisco is a major transportation hub in California with easy highway access to cities across the US. Browse 72 driving routes from San Francisco including popular destinations like Sacramento, San Jose, Reno. Find exact drive times, distances, and estimated gas costs.
72 destinations sorted by distance
San Francisco is a popular starting point for road trips across the United States, with 74 destinations reachable by car. Whether you are planning a quick day trip to a neighboring city or an extended cross-country adventure, this page provides accurate driving times, distances, and estimated fuel costs for every route. Use the cards above to compare drive times and pick the best destination for your next trip. Each route page includes detailed information about highway options, toll costs, traffic patterns, and the best times to travel.