Des Moines, IA

Iowa

25
Destinations

Des Moines, IA is a gateway to great road trips in 25 driving routes available. Browse 25 routes with drive times, distances, and gas costs.

Driving Times from Des Moines, IA

25 destinations

Medium Trips — 1

Jefferson City, MO
288 miles
5h 14min

Long Distance — 24

Albany, NY
1324 miles
24h 4min
Annapolis, MD
1195 miles
21h 43min
Atlanta, GA
961 miles
17h 28min
Augusta, ME
1581 miles
28h 44min
Austin, TX
1059 miles
19h 15min
Baton Rouge, LA
1015 miles
18h 27min
Bismarck, ND
657 miles
11h 56min
Boise, ID
1499 miles
27h 15min
Boston, MA
1504 miles
27h 20min
Carson City, NV
1795 miles
32h 38min
Charleston, WV
874 miles
15h 53min
Cheyenne, WY
755 miles
13h 43min
Columbia, SC
1121 miles
20h 22min
Columbus, OH
736 miles
13h 22min
Concord, NH
1468 miles
26h 41min
Denver, CO
791 miles
14h 22min
Dover, DE
1255 miles
22h 49min
Frankfort, KY
675 miles
12h 16min
Harrisburg, PA
1140 miles
20h 43min
Hartford, CT
1402 miles
25h 29min
Helena, MT
1266 miles
23h 1min
Indianapolis, IN
534 miles
9h 42min
Jackson, MS
869 miles
15h 48min
Juneau, AK
2733 miles
49h 41min

Frequently Asked Questions

How far is Des Moines, IA from Albany, NY?
Des Moines, IA is approximately 288 miles from Jefferson City, MO, taking around 5h 14m.
What cities are within 3 hours of Des Moines, IA?
There are 0 cities within 3 hours, including nearby cities.
How many routes from Des Moines, IA?
Des Moines, IA has 25 routes in our database.

How Far Is Des Moines, IA from Major Cities?

Approximate road distances and non-stop drive times from Des Moines, IA to nearby major cities. The closest major hub is Omaha, roughly 145 miles away by road.

Omaha~145 mi · 2h 30m
Kansas City~215 mi · 3h 45m
Minneapolis~280 mi · 4h 45m
St Louis~330 mi · 5h 45m
Milwaukee~370 mi · 6h 30m

Estimates assume typical highway speeds without extended stops; actual times vary with traffic and weather.

Nearest Major Airports to Des Moines, IA

If part of the trip is by air, these are the closest major airports to Des Moines, IA by road:

Des Moines (DSM)~5 mi · 15 min
Omaha Eppley (OMA)~145 mi · 2h 30m

Airport drive times are door-to-terminal estimates — add time for parking and security.

Driving from Des Moines, IA: What to Know

Des Moines, IA, Iowa makes a practical base for exploring the Midwest by car. Before a longer trip, give the vehicle a quick once-over — tire pressure, washer fluid, and wipers — and download offline maps, as coverage can thin out between towns on rural stretches. The main corridor for trips listed on this page is I-95, so check for construction or closures on that route before setting out.

All drive times on this page assume normal conditions. Gas cost estimates use a 30 MPG vehicle at current average fuel prices — a hybrid or EV can cut that cost roughly in half, and you can compare electric options on our EV trip pages.

Road Trips from Des Moines IA

Looking to hit the road from Des Moines IA? Browse 27 driving routes with detailed travel data including estimated drive times, mileage, and gas costs. From short trips under an hour to epic multi-day drives, Des Moines IA connects to destinations across the country. Click any route card for a full breakdown of the journey, including suggested stops, traffic estimates, toll information, and the recommended time of day to depart for the smoothest drive.